Clonidine is the generic name of Catapres, a medication used to treat high blood pressure. Clonidine works by slowing down your heart rate and relaxing blood vessels. For some children, a combination of a mood stabilizer and one of the newer atypical anti-psychotic medications may be required in order to control rage and aggression, provide adequate mood stabilization, and control any psychotic symptoms, if present. Lamotrigine: A Depression Mood Stabilizer. Lamotrigine, an anticonvulsant drug is one such widely studied medication whose therapeutic efficacy has been extended even beyond its use as a mood stabilizer (Bowden and Singh, 2012). They did work. I just couldn't tolerate the side effects some of which are statistically rare so there's no point discussing them. As for Clonidine its primary use in me is in controlling dystonic spasms but it does work as a mood stabilizer. For myself, the mood stabilizer I take Clonidine causes weight gain. I bought some chocolates today and I had already eaten dessert. I was going to snack on them anyway but I told myself not to or the weight gain would start so I didn't. I'm thinking about them now but they are for tomorrow. I've been in positions where I was on meds that caused weight gain or weight loss. Mood disorders such as anxiety, depression, bipolar disorder, borderline personality disorder, and others can practically cripple a person’s quality of life and severely affect their day-to-day ability to function normally, let alone optimally, in society. Some doctors start instead with either clonidine or guanfacine plus one of the following mood stabilizers: lithium, carbamazepine, valproic acid, or lamotrigine. advertisement Once the patient is stable on therapeutic doses, a stimulant can be added if ADHD symptoms remain; if necessary, an antidepressant is sometimes added as well. Summary. Mood stabilizer is found among people who take Clonidine, especially for people who are female, 10-19 old , have been taking the drug for 1 month, also take medication Strattera, and have Depression. I was on Clonidine and couldn't tolerate it. I was taking it for spasms from tardive dystonia as well as a mood stabilizer. Some people find it tolerable though. I was not able to tolerate Keppra because of personality changes and its not used often for this exact reason. The mood stabilizer I take now Clonidine is rarely used because it can cause depression and its a blood pressure medication in its original use with the potential of some severe side effects.